There have been many ongoing trials on this topic and they are finally starting to conclude that intervening early, even when the patient is asymptomatic, is beneficial once echocardiogram shows the patient has severe aortic stenosis. A meta-analysis of 4 randomized control trials on this topic recently showed that among 1,400 patients at 42-74 months of follow up, those who received TAVR or other valve replacement were significantly less likely to experience death, stroke, h

We get a lot of questions from women who would benefit from vaginal/topical estrogen but are appropriately concerned about increased risk for heart attack and stroke with estrogen supplementation. A new study in the journal Stroke suggests that even amongst women who would be high or above average risk for stroke, use of vaginal estradiol was not associated with excess risk for recurrent ischemic stroke in this population. And this was true at doses as high as > 50ug per we

This is one of the most commonly asked questions that we get and probably one of the most difficult to manage as really >95% of it is behavioral and/or anxiety related and not truly a neurologic problem with sleep…   There was a really great recent New England Journal of Medicine review article on this topic that does a nice job of describing the evidence behind the thoughts on this subject. [1]   In brief, the majority of patient reported insomnia falls into one of (or a com

Interestingly, as with all things in medicine, there may not be a right answer to this question. One intriguing study showed this was...

We are getting a lot of questions as to if/when COVID-19 vaccination is recommend. Everyone’s individual healthcare should be...

US judge sides with FDA's removal of Lilly's weight loss drug from shortage list https://www.reuters.com/business/healthcare-pharmaceuticals/us-judge-sides-with-fdas-removal-lillys-weight-loss-drug-shortage-list-2025-05-07/

Interesting summary of some recent studies that have shown decreased incident of dementia / alzheimer's disease in patients who got the...

It appears for now anyway Ozempic / Wegovy / Zepbound / Monjuro will not be covered by medicare: Medicare and Medicaid won’t pay for popular obesity drugs like Wegovy and Zepbound, rejecting, at least for now, a Biden administration proposal that would have expanded coverage for weight loss https://www.wsj.com/health/healthcare/trump-administration-rejects-expanding-medicare-medicaid-coverage-of-obesity-drugs-f32ced38?st=pZanPk&reflink=article_gmail_share

Great artcile from the Wall Street Journal on this 'hot topic.' Admittedly I have never heard about this until recently patients have...

Great article in the Wallstreet journal on 'longevity science': https://www.wsj.com/health/wellness/longevity-antiaging-leonard-guarente-...

I get asked this all the time. No great data on this yet given these drugs are new. Some evidence for weight re-gain. An interesting article here: https://www.wsj.com/health/wellness/a-year-after-i-stopped-taking-a-weight-loss-drug-ive-lost-20-more-pounds-b23c09e6?st=nKaXEA&reflink=article_gmail_share Anecdotally, if you can use the time you are on the drug to 'retrain' your brain and body to learn how much food your body actually needs, you can behaviorally control the calor

Great piece, I think about this topic a lot: https://www.wsj.com/health/healthcare/we-are-turning-too-many-people-into-medical-patients-a...

Compounded versions of Semaglutide (Ozempic / Wegovy) and Tirzepitide (Monjuro and Zepbound) are no longer legal, with further FDA...

The Wall Street Journal (WSJ) has been writing about this topic frequently lately it seems, which I am glad to see. I have been espousing...

This is a complex and evolving topic, generating a ton of calls and interest to us. There are multiple moving parts to this, and here is...

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Link to the article here: https://www.reuters.com/business/healthcare-pharmaceuticals/drug-compounders-sue-us-fda-over-removal-wegovy-ozempic-shortage-list-2025-02-24/

See article here: https://www.fiercehealthcare.com/health-tech/fda-declares-semaglutide-shortage-over-spelling-end-compounded-glp-1-market

I have been preaching this to patients for many years, that any purported benefit for long-term use of benzodiazepines such as Ativan,...

FDA Announced Removal of Tirzepatide from the Drug Shortage List https://search.app/1tgc1KWT5tQ1BPyQA